Pharmaceutical use raw material Dexamethasone white crystal powder for Anti Inflammatory no 50-02-2
Dexamethasone Basic Info
Product Name Dexamethasone
Molecular Formula C22H29FO5
Molecular Weight 392.46
Appearance White crystalline solid
Product Categories Active Pharmaceutical Ingredients;Antitumors for Research and Experimental Use;Biochemistry;Hydroxyketosteroids;Steroids;Intermediates & Fine Chemicals;Pharmaceuticals;Isotope Labeled Compounds;Steroid and Hormone;Pharmaceutical intermediate;API;MAXIDEX;Hormone Drugs
Mol File 50-02-2.mol
Mp 262-264 °C(lit.)
Alpha 75 º (c=1, dioxane)
refractive index 76 ° (C=1, Dioxane)
storage temp 2-8°C
Solubility ethanol: 1 mg/mL
Water Solubility 10 mg/100 mL (25 ºC)
Stability Stable,Combustible. Incompatible with strong oxidizing agents, strong bases, acid anhydrides, acid chlorides. May be light sensitive.
NIST Chemistry Reference Prednisolone, 9alpha-fluoro-16alpha-methyl-(50-02-2)
EPA Substance Registry System Pregna-1,4-diene- 3,20-dione, 9-fluoro-11,17,21-trihydroxy- 16-methyl-, (11.beta.,16.alpha.)-(50-02-2)
Quality Standards CP2005/USP/BP/EP
Dexamethasone is a steroid but not the kind that build muscle, meaning: is not an anabolic steroid. It is a very potent anti-inflammatory and immunosuppressant synthetic glucocorticoid used to treat allergic conditions, dermatologic diseases, endocrine problems, regional enteritis, ulcerative colitis, acute exacerbations of Multiple Sclerosis, Rheumatic disorders. This is a prescription drug, which must be taken exactly as the doctor prescribed it, should be tapered gradually because if you discontinue using it all the sudden, it gives you Corticosteroid withdrawal symptoms due to an acute adrenal crisis, which is a life-threatening condition.
Decadron is used to treat conditions such as arthritis, blood/hormone/immune system disorders, allergic reactions, certain skin and eye conditions, breathing problems, certain bowel disorders. Also it is used in the treatment of cancers of the white blood cells (leukemias), and lymph gland cancers (lymphomas). Finally, Decadron is used as replacement therapy in patients whose adrenal glands are unable to produce sufficient amounts of corticosteroids.
Product name Dexamethasone
Appearance White crystalline powder
Chromatographic purity Any individual impurity not more than 1.0% Total impurities not more than 2.0% 0.27% 0.7%
Loss on drying Not more than 0.5% 0.1%
Residue on ignition Not more than 0.2% 0.1%
Residual solvents Methanol≤3000ppm Methylene Chloride≤600ppm Chloroform≤60ppm Tetrahydrofuran≤720ppm 350ppm Not detect out Not detect out Not detect out
Assay Between 97.0% and 102.0% 99.2%
Micronixation 90% not more than 10 microns 90% not more than 10 aicrons
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