Appearance:Light yellow powder
Grade: Pharma Grade
Usage:Diosmin is the semi-synthesis product of Hesperidin, which used in treating the chronic venous insufficiency and acute naevus. It is also a new potential anticancer API
Diosmin is a chemical found in citrus fruits and Scrophularia nodosa, it is also a semisynthetic drug (modified hesperidin), a member of the flavonoid family.
It is an oral phlebotropic drug used in the treatment of venous disease, i.e., chronic venous insufficiency (CVI) and hemorrhoidal disease (HD), in acute or chronic hemorrhoids, in place of rubber-band ligation, in combination with fiber supplement, or as an adjuvant therapy to hemorrhoidectomy, in order to reduce secondary bleeding. To control internal symptoms of hemorrhoids (piles), it is used with hesperidin. Clinical studies have been inconclusive and no review articles on its use in vascular disease have been published.
Diosimin has vitamin P sample effect, can reduce the permeability of blood vessle brittleness and abnormal, and used in the adjuvant treatment of prevention and control of high blood pressure and hardening of the arteries, and also used in the treatment of blood caplliary brittleness , in which had a better effection than rutin, hesperidin, and has the characteristics of low toxicity.
Indications and Uses
Diosmin is an anti-inflammatory and a flavonoid glycoside that reduces venous hyperpressure. Diosmin also reduces capillary hyperpermeability and expression of endothelial adhesion molecules (ICAM1, VCAM1). Diosmin effectively inhibits the P-glycoprotein (Pgp)-mediated efflux in cells.
Diosmin is currently a prescription medication in some European countries, and is sold as a nutritional supplement in the United States and the rest of Europe.
Diosmin is used for treating various disorders of blood vessels including hemorrhoids, varicose veins, poor circulation in the legs (venous stasis),and bleeding (hemorrhage) in the eye or gums. It is also used to treat swelling of the arms (lymphedema) following breast cancer surgery, and to protect against livertoxicity. It is often taken in combination with hesperidin, another plantchechemical.
1. Reduce the brittleness of blood vessel and abnormal permeability
2. It may prevent high blood pressure and hardening of the arteries auxiliary treatment.
3. It may treat effectively hemorrhoids and Chronic venous dysfunction
1.It has vitamin Peffectand can reduce the brittlenessof blood vessel and abnormal permeability
2.It may prevent hight blood pressure and hardening of the arteries auxiliary treatment.
3.It may treat effectively hemorrhoidsand Chronic venousdysfunction